000	02206cam  2200361zi 4500
001	9.873823
003	CaOODSP
005	20221107164026
006	m     o  d f
007	cr |n|||||||||
008	190529s1989    oncd   #ot   f000 0 eng d
040	|aCaOODSP|beng|erda|cCaOODSP
041	|aeng|bfre
043	|an-cn---
086	1 |aEn13-5/89-130E-PDF
100	1 |aSherry, J. P., |eauthor.
245	10|aDimethyl sulfoxide as solubilization agent in the radioimmunoassay for the detection of polychlorinated dibenzo-p-dioxins / |cby J.P. Sherry [and three others].
264	1|aBurlington, Ontario : |bResearch and Applications Branch, National Water Research Institute, |c[1989]
300	|a1 online resource (ii, ii, 16 pages) : |bfigures.
336	|atext|btxt|2rdacontent
337	|acomputer|bc|2rdamedia
338	|aonline resource|bcr|2rdacarrier
490	1 |aNWRI contribution ; |vno. 89-130
500	|aDigitized edition from print [produced by Environment and Climate Change Canada].
504	|aIncludes bibliographical references.
520	|a"Immunoassays are potentially valuable tools for use in screening environmental samples for a broad range of contaminants, such as polychlorinated dibenzo-p-dioxins (PCDDs). The performance of the RIA for PCDDs was characterized using 4 solubilization systems: Cutscum, Triton, horse serum, and dimethylsulfoxide (DMSO). The DMSO based assay appeared to perform best at low PCDD levels. The effects of assay incubation time and hapten storage conditions on the DMSO based assay were assessed. The separation of bound from unbound radioactivity was accelerated without adversely affecting assay performance. Further assay development through the use of an improved hapten is considered"--Abstract.
546	|aIncludes abstract in French.
692	07|2gccst|aWater pollution
710	1 |aCanada. |bEnvironment Canada.
710	2 |aNational Water Research Institute (Canada). |bResearch and Applications Branch.
830	#0|aNWRI contribution ;|vno. 89-130.|w(CaOODSP)9.844121
856	40|qPDF|s1.24 MB|uhttps://publications.gc.ca/collections/collection_2019/eccc/en13-5/En13-5-89-130-eng.pdf