00000nam 2200000za 4500 9.821161 CaOODSP 20240219183435 cr ||||||||||| 160715s2010 onc|||||o f000 0 eng d CaOODSP eng eng fre n-cn--- D68-4/203-2010E-PDF Ford, B. N. Microarray systems for microbial detection and identification [electronic resource] / by B.N. Ford and D.E. Bader. [Ottawa] : Defence Research and Development Canada, c2010. viii, 38 p. : figures, graphs, tables. Technical report ; 2010-203 "December 2010." Includes bibliographical references. The relatively recent availability of complete or near-complete sequences of microbial DNA makes it possible to find and exploit unique genetic markers for most microbes. Using microbial genome sequences from public databases, a high-density microarray system has been developed which should enable the identification of hundreds of individual species or strains of pathogenic microorganisms on a single assay platform. This report summarizes the design, development, and testing of this microarray design. The system is currently capable of discriminating multiple human pathogens, Category A biothreats, and some agricultural pathogens, other using supervised analysis methods. Ongoing development will include tools for automation of analysis, and extension of the testing panel of microbes. gccst Technical reports Genomic fingerprinting Microbe Microarray Bader, Douglas E. (Douglas Edward), 1960- Defence R&D Canada. Technical report (Defence R&D Canada) 2010-203 (CaOODSP)9.820558 PDF 1.52 MB https://publications.gc.ca/collections/collection_2016/rddc-drdc/D68-4-203-2010-eng.pdf