00000nam 2200000za 4500 9.847691 CaOODSP 20221107153509 cr ||||||||||| 171123s2018 onc o f000 0 eng d 9780660239996 9780660240008 CaOODSP eng n-cn--- NR16-181/2017E-PDF Increased viral production (L-12392) [electronic resource]. [Ottawa] : National Research Council Canada, [2018] [1] p. Issued also in French under title: Production augmentée de virus (L-12392). Caption title. "December 2017." “Viruses are often used with mammalian cell culture systems as live factories for the production of biologics such as recombinant proteins and vaccines. A common example is the use of human embryonic kidney (HEK 293) cells to produce adenovirus that expresses the gene of interest. The use of expression systems provides flexibility in determining the conditions under which virus production can be optimized. The NRC has developed a simple, cost-effective and scalable method suitable for both research and commercial scale production that enhances adenovirus production by applying osmotic stress to host HEK293 cells”--Highlights. Issued also in print format. Adenoviruses Cultures and culture media HEK293 Cells National Research Council Canada. Production augmentée de virus (L-12392) (CaOODSP)9.847694 Increased viral production (CaOODSP)9.847692 PDF 116 KB https://publications.gc.ca/collections/collection_2018/cnrc-nrc/NR16-181-2017-eng.pdf