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| 001 | 9.847691 |
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| 003 | CaOODSP |
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| 005 | 20221107153509 |
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| 007 | cr ||||||||||| |
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| 008 | 171123s2018 onc o f000 0 eng d |
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| 020 | |a9780660239996|z9780660240008 |
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| 040 | |aCaOODSP|beng |
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| 043 | |an-cn--- |
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| 086 | 1 |aNR16-181/2017E-PDF |
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| 245 | 00|aIncreased viral production (L-12392) |h[electronic resource]. |
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| 260 | |a[Ottawa] : |bNational Research Council Canada, |c[2018] |
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| 300 | |a[1] p. |
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| 500 | |aIssued also in French under title: Production augmentée de virus (L-12392). |
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| 500 | |aCaption title. |
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| 500 | |a"December 2017." |
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| 520 | |a“Viruses are often used with mammalian cell culture systems as live factories for the production of biologics such as recombinant proteins and vaccines. A common example is the use of human embryonic kidney (HEK 293) cells to produce adenovirus that expresses the gene of interest. The use of expression systems provides flexibility in determining the conditions under which virus production can be optimized. The NRC has developed a simple, cost-effective and scalable method suitable for both research and commercial scale production that enhances adenovirus production by applying osmotic stress to host HEK293 cells”--Highlights. |
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| 530 | |aIssued also in print format. |
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| 693 | 4|aAdenoviruses |
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| 693 | 4|aCultures and culture media |
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| 693 | 4|aHEK293 Cells |
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| 710 | 2 |aNational Research Council Canada. |
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| 775 | 08|tProduction augmentée de virus (L-12392) |w(CaOODSP)9.847694 |
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| 776 | 0#|tIncreased viral production |w(CaOODSP)9.847692 |
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| 856 | 40|qPDF|s116 KB|uhttps://publications.gc.ca/collections/collection_2018/cnrc-nrc/NR16-181-2017-eng.pdf |
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