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| 02240cam 2200385zi 4500 |
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001 | 9.880700 |
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003 | CaOODSP |
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005 | 20221107165838 |
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006 | m o d f |
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007 | cr |n||||||||| |
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008 | 191017t20182018onc ob f000 0 eng d |
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040 | |aCaOODSP|beng|erda|cCaOODSP |
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043 | |an-cn--- |
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086 | 1 |aD68-10/084-2018E-PDF |
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100 | 1 |aBhatti, Junaid, |eauthor. |
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245 | 10|aSystematic review of human and animal studies examining the efficacy and safety of N-acetylcysteine (Nac) and N-acetylcysteine amide (Naca) in traumatic brain injury : |bimpact on neurofunctional outcome and biomarkers of oxidative stress and inflammation / |cJunaid Bhatti [and six others]. |
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264 | 1|aToronto, Ontario : |bDRDC - Toronto Research Centre, Defence Research and Development Canada, |c2018. |
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264 | 4|c©2018 |
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300 | |a1 online resource (14 pages, 2 unnumbered pages) |
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336 | |atext|btxt|2rdacontent |
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337 | |acomputer|bc|2rdamedia |
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338 | |aonline resource|bcr|2rdacarrier |
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490 | 1 |aExternal literature (P) ; |vDRDC-RDDC-2018-P084 |
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500 | |a"Can unclassified." |
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500 | |a"June 2018." |
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500 | |a"Journal of Frontiers in Neurology, doi: 10.3389/fneur.2017.00744, Volume 8, Article 744." |
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500 | |a"Date of publication from Ext publisher: January 2018." |
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504 | |aIncludes bibliographical references (pages 12-14). |
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520 | |a"No new therapies for traumatic brain injury (TBI) have been officially translated into current practice. At the tissue and cellular level, both inflammatory and oxidative processes may be exacerbated post-injury and contribute to further brain damage. N-acetylcysteine (NAC) has the potential to downregulate both processes. This review focuses on the potential neuroprotective utility of NAC and N-acetylcysteine amide (NACA) post-TBI"--Background, page 1. |
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692 | 07|2gccst|aInjuries |
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692 | 07|2gccst|aMedical research |
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710 | 1 |aCanada. |bDefence R&D Canada. |
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710 | 2 |aDefence R&D Canada. |bToronto Research Centre. |
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830 | #0|aExternal literature (P) (Defence R&D Canada)|vDRDC-RDDC-2018-P084.|w(CaOODSP)9.854437 |
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856 | 40|qPDF|s803 KB|uhttps://publications.gc.ca/collections/collection_2019/rddc-drdc/D68-10-084-2018-eng.pdf |
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