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| 01970cam 2200325za 4500 |
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| 001 | 9.821161 |
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| 003 | CaOODSP |
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| 005 | 20221107143405 |
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| 007 | cr ||||||||||| |
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| 008 | 160715s2010 onc|||||o f000 0 eng d |
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| 040 | |aCaOODSP|beng |
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| 041 | |aeng|bfre |
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| 043 | |an-cn--- |
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| 086 | 1 |aD68-4/203-2010E-PDF |
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| 100 | 1 |aFord, B. N. |
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| 245 | 10|aMicroarray systems for microbial detection and identification |h[electronic resource] / |cby B.N. Ford and D.E. Bader. |
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| 260 | |a[Ottawa] : |bDefence Research and Development Canada, |cc2010. |
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| 300 | |aviii, 38 p. : |bfigures, graphs, tables. |
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| 490 | 1 |aTechnical report ; |v2010-203 |
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| 500 | |a"December 2010." |
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| 504 | |aIncludes bibliographical references. |
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| 520 | |aThe relatively recent availability of complete or near-complete sequences of microbial DNA makes it possible to find and exploit unique genetic markers for most microbes. Using microbial genome sequences from public databases, a high-density microarray system has been developed which should enable the identification of hundreds of individual species or strains of pathogenic microorganisms on a single assay platform. This report summarizes the design, development, and testing of this microarray design. The system is currently capable of discriminating multiple human pathogens, Category A biothreats, and some agricultural pathogens, other using supervised analysis methods. Ongoing development will include tools for automation of analysis, and extension of the testing panel of microbes. |
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| 692 | 07|2gccst|aTechnical reports |
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| 693 | 4|aGenomic fingerprinting |
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| 693 | 4|aMicrobe |
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| 693 | 4|aMicroarray |
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| 700 | 1 |aBader, Douglas E. |q(Douglas Edward), |d1960- |
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| 710 | 1 |aCanada. |bDefence R&D Canada. |
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| 830 | #0|aTechnical report (Defence R&D Canada)|v2010-203|w(CaOODSP)9.820558 |
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| 856 | 40|qPDF|s1.52 MB|uhttps://publications.gc.ca/collections/collection_2016/rddc-drdc/D68-4-203-2010-eng.pdf |
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