| 000 | 00000nam 2200000za 4500 |
| 001 | 9.821161 |
|---|
| 003 | CaOODSP |
|---|
| 005 | 20240219183435 |
|---|
| 007 | cr ||||||||||| |
|---|
| 008 | 160715s2010 onc|||||o f000 0 eng d |
|---|
| 040 | |aCaOODSP|beng |
|---|
| 041 | |aeng|bfre |
|---|
| 043 | |an-cn--- |
|---|
| 086 | 1 |aD68-4/203-2010E-PDF |
|---|
| 100 | 1 |aFord, B. N. |
|---|
| 245 | 10|aMicroarray systems for microbial detection and identification |h[electronic resource] / |cby B.N. Ford and D.E. Bader. |
|---|
| 260 | |a[Ottawa] : |bDefence Research and Development Canada, |cc2010. |
|---|
| 300 | |aviii, 38 p. : |bfigures, graphs, tables. |
|---|
| 490 | 1 |aTechnical report ; |v2010-203 |
|---|
| 500 | |a"December 2010." |
|---|
| 504 | |aIncludes bibliographical references. |
|---|
| 520 | |aThe relatively recent availability of complete or near-complete sequences of microbial DNA makes it possible to find and exploit unique genetic markers for most microbes. Using microbial genome sequences from public databases, a high-density microarray system has been developed which should enable the identification of hundreds of individual species or strains of pathogenic microorganisms on a single assay platform. This report summarizes the design, development, and testing of this microarray design. The system is currently capable of discriminating multiple human pathogens, Category A biothreats, and some agricultural pathogens, other using supervised analysis methods. Ongoing development will include tools for automation of analysis, and extension of the testing panel of microbes. |
|---|
| 692 | 07|2gccst|aTechnical reports |
|---|
| 693 | 4|aGenomic fingerprinting |
|---|
| 693 | 4|aMicrobe |
|---|
| 693 | 4|aMicroarray |
|---|
| 700 | 1 |aBader, Douglas E. |q(Douglas Edward), |d1960- |
|---|
| 710 | 2 |aDefence R&D Canada. |
|---|
| 830 | #0|aTechnical report (Defence R&D Canada)|v2010-203|w(CaOODSP)9.820558 |
|---|
| 856 | 40|qPDF|s1.52 MB|uhttps://publications.gc.ca/collections/collection_2016/rddc-drdc/D68-4-203-2010-eng.pdf |
|---|