00000nam 2200000za 4500 9.827958 CaOODSP 20221107144929 cr ||||||||||| 170519s2017 quc ob f000 0 eng d 978-0-660-06864-0 978-0-660-07088-9 CaOODSP eng n-cn--- En49-7/1-44-2016E-PDF En49-7/1-44-2016E Guidance document for testing the pathogenicity and toxicity of new microbial substances to aquatic and terrestrial organisms [electronic resource]. 2nd ed., December 2016. Gatineau, QC : Environment and Climate Change Canada, c2017. xxxii, 176 p. Report ; EPS 1/RM/44 Issued also in French under title: Guide des essais de pathogénicité et de toxicité de nouvelles substances microbiennes pour les organismes aquatiques et terrestres. Co-authors: D. McLeay ... et al; 2nd edition prepared by Ryan Hennessy. Cf. Acknowledgements. Includes bibliographical references (p. 158-168). “The intent of this document is to provide guidance on preparing for and conducting single-species tests to measure and evaluate the pathogenicity and/or toxicity of new microbial substances to aquatic and terrestrial organisms. It focuses on the information requirements with respect to laboratory tests for measuring the potential ecological effects of new microbial substances on the following six categories of test (host) organisms, that might be required by Environment and Climate Change Canada as part of the New Substances Notification (NSN) Regulations under the Canadian Environmental Protection Act, 1999: (1) an aquatic plant; (2) an aquatic invertebrate; (3) an aquatic vertebrate; (4) a terrestrial plant; (5) a terrestrial invertebrate; and (6) a terrestrial vertebrate. The guidance herein is intended for notifiers, environmental consultants, study directors, and principal investigators. It will assist in the selection of an appropriate series of biological test methods for measuring the pathogenicity and/or toxicity of new microbial substances, as well as in the planning, execution, and reporting phases associated with each test. Changes introduced in this second edition of the guidance have primarily come from microbial substance testing experience in Environment and Climate Change Canada research laboratories and improvements in test methodologies over the past decade”--Abstract, p. ii. Issued also in print format. gccst Microorganisms gccst Bioassay gccst Toxicology gccst Methodology gccst Standards McLeay, D. J. (Donald James), 1943- Hennessy, Ryan. Canada. Environment and Climate Change Canada. Guide des essais de pathogénicité et de toxicité de nouvelles substances microbiennes pour les organismes aquatiques et terrestres (CaOODSP)9.827963 Guidance document for testing the pathogenicity and toxicity of new microbial substances to aquatic and terrestrial organisms (CaOODSP)9.829341 Guidance document for testing the pathogenicity and toxicity of new microbial substances to aquatic and terrestrial organisms / (CaOODSP)9.560493 PDF 1.58 MB https://publications.gc.ca/collections/collection_2017/eccc/En49-7-1-44-2016-eng.pdf