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| 001 | 9.858145 |
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| 003 | CaOODSP |
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| 005 | 20241203113643 |
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| 007 | cr ||||||||||| |
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| 008 | 180626s2001 quc o f00| 0 eng d |
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| 040 | |aCaOODSP|beng |
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| 041 | |aeng|bfre |
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| 043 | |an-cn--- |
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| 086 | 1 |aCW69-5/339E-PDF |
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| 100 | 1 |aTrudeau, S. |
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| 245 | 12|aA method to determine cytochrome P4501A activity in wildlife microsomes |h[electronic resource] / |cS.F. Trudeau and F.J. Maisonneuve. |
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| 260 | |aHull, Quebec : |bCanadian Wildlife Service, Headquarters, |c2001. |
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| 300 | |a[59] p. |
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| 490 | 1 |aTechnical report series ; |vno. 339 |
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| 500 | |aDigitized edition from print [produced by Environment and Climate Change Canada]. |
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| 500 | |aCo-published by: National Wildlife Research Centre. |
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| 504 | |aIncludes bibliographical references. |
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| 520 | |a"The Biomarker Laboratory (Laboratory Services Section) of the National Wildlife Research Centre (NWRC) has been providing biochemical analyses (biomarkers) in wildlife tissues in support of its National Wildlife Toxicology Program since the early 1990s. Induction of cytochrome P4S01A is a sensitive biomarker of exposure to environmental contaminants such as PARs and HAHs. Measurement of the cytochrome P450-associated enzyme, 7-ethoxyresorufin-O-deethysase (EROD), is the most common method to evaluate the activity of the P4501A system. This report contains a detailed description of a fluorescent spectrophotometric method (MET-lBMK-EROD-01), to measure the product of the EROD reaction (resorufin) and total protein simultaneously, using a plate reader"--Pref. |
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| 530 | |aIssued also in print format. |
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| 546 | |aIncludes preface in French. |
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| 692 | 07|2gccst|aWildlife |
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| 692 | 07|2gccst|aPollution control |
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| 693 | 4|aMicrosomes |
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| 693 | 4|aCytochrome P-450 |
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| 700 | 1 |aMaisonneuve, F. J. |
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| 710 | 1 |aCanada. |bEnvironment Canada. |
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| 710 | 1 |aCanadian Wildlife Service. |bHeadquarters. |
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| 710 | 2 |aNational Wildlife Research Centre (Canada) |
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| 776 | 0#|tA method to determine cytochrome P4501A activity in wildlife microsomes / |w(CaOODSP)9.614888 |
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| 830 | #0|aTechnical report series (Canadian Wildlife Service)|vno. 339.|w(CaOODSP)9.504438 |
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| 856 | 40|qPDF|s1.73 MB|uhttps://publications.gc.ca/collections/collection_2018/eccc/cw69-5/CW69-5-339-eng.pdf |
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