00000nam 2200000zi 4500 9.926208 CaOODSP 20230901142143 m o d f cr |n||||||||| 230815s1991 nscad ob f000 0 eng d CaOODSP eng rda CaOODSP n-cn--- DR52-4/11-1991E-PDF National Research Council of Canada. Atlantic Research Laboratory‏, author. Development of high-resolution separatory techniques and mass spectrometric methods for the verification of saxitoxin and tetrodotoxin in water and soil / interim report prepared for Paul A. D'Agostino by Institute for Marine Biosciences, National Research Council. Halifax, Nova Scotia : Institute for Marine Biosciences, National Research Council ; Ralston, Alberta : Defence Research Establishment Suffield, 1991 1 online resource (15, [14] pages) : illustrations, charts text txt rdacontent computer c rdamedia online resource cr rdacarrier Contract report (DRES) ; 32-91 Digitized edition from print [produced by Defence Research and Development Canada]. Includes bibliographical references (pages 14-15). "Nature produces many compounds that are highly toxic to humans. Among the most toxic are certain metabolites produced by marine organisms; these include saxitoxin (STX), a member of a related family of compounds responsible for paralytic shellfish poisoning (PSP, the "red-tide" shellfish poisoning), and tetrodotoxin (TTX), the puffer fish toxin. These toxins have been recognized by the UN as potential chemical warfare agents. It is important therefore to have available analytical methods for verification procedures with respect to chemical warfare controls agreements. The extremely high toxicity of these marine toxins implies that such analytical methods must be capable of detecting, identifying, and if possible quantifying, the target compounds present at trace levels in complex matrices. [...] The present document thus represents an interim report on work done at IMB on instrumental techniques for trace analysis of these highly polar, thermally labile toxins"--page 1. Marine toxins Analysis. Chemical agents (Munitions) Saxitoxin. Tetrodotoxin. Toxines marines Analyse. Agents chimiques (Munitions) Saxitoxine. Tétrodotoxine. D’Agostino, Paul Anthony, recipient. Defence Research Establishment Suffield, issuing body. Contract report (DRES) 32-91. (CaOODSP)9.926097 PDF 2.06 MB https://publications.gc.ca/collections/collection_2023/rddc-drdc/DR52-4-11-1991-eng.pdf DRES-CR-32-91