Microarray systems for microbial detection and identification / by B.N. Ford and D.E. Bader.: D68-4/203-2010E-PDF
The relatively recent availability of complete or near-complete sequences of microbial DNA makes it possible to find and exploit unique genetic markers for most microbes. Using microbial genome sequences from public databases, a high-density microarray system has been developed which should enable the identification of hundreds of individual species or strains of pathogenic microorganisms on a single assay platform. This report summarizes the design, development, and testing of this microarray design. The system is currently capable of discriminating multiple human pathogens, Category A biothreats, and some agricultural pathogens, other using supervised analysis methods. Ongoing development will include tools for automation of analysis, and extension of the testing panel of microbes.
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| Department/Agency | Defence R&D Canada. |
|---|---|
| Title | Microarray systems for microbial detection and identification / by B.N. Ford and D.E. Bader. |
| Series title | Technical report ; 2010-203 |
| Publication type | Series - View Master Record |
| Language | [English] |
| Format | Electronic |
| Electronic document | |
| Note(s) | "December 2010." Includes bibliographical references. |
| Publishing information | [Ottawa] : Defence Research and Development Canada, c2010. |
| Author / Contributor | Ford, B. N. Bader, Douglas E. (Douglas Edward), 1960- |
| Description | viii, 38 p. : figures, graphs, tables. |
| Catalogue number |
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| Subject terms | Technical reports Genomic fingerprinting Microbe Microarray |
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