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Systematic review of human and animal studies examining the efficacy and safety of N-acetylcysteine (Nac) and N-acetylcysteine amide (Naca) in traumatic brain injury : impact on neurofunctional outcome...D68-10/084-2018E-PDF

"No new therapies for traumatic brain injury (TBI) have been officially translated into current practice. At the tissue and cellular level, both inflammatory and oxidative processes may be exacerbated post-injury and contribute to further brain damage. N-acetylcysteine (NAC) has the potential to downregulate both processes. This review focuses on the potential neuroprotective utility of NAC and N-acetylcysteine amide (NACA) post-TBI"--Background, page 1.

Permanent link to this Catalogue record:
publications.gc.ca/pub?id=9.880700&sl=0

Publication information
Department/Agency
  • Defence R&D Canada.
  • Defence R&D Canada. Toronto Research Centre.
TitleSystematic review of human and animal studies examining the efficacy and safety of N-acetylcysteine (Nac) and N-acetylcysteine amide (Naca) in traumatic brain injury : impact on neurofunctional outcome and biomarkers of oxidative stress and inflammation / Junaid Bhatti [and six others].
Series title
  • External literature (P) ; DRDC-RDDC-2018-P084
Publication typeMonograph - View Master Record
Language[English]
FormatDigital text
Electronic document
Note(s)
  • "Can unclassified."
  • "June 2018."
  • "Journal of Frontiers in Neurology, doi: 10.3389/fneur.2017.00744, Volume 8, Article 744."
  • "Date of publication from Ext publisher: January 2018."
  • Includes bibliographical references (pages 12-14).
Publishing information
  • Toronto, Ontario : DRDC - Toronto Research Centre, Defence Research and Development Canada, 2018.
  • ©2018
Author / Contributor
  • Bhatti, Junaid, author.
Description1 online resource (14 pages, 2 unnumbered pages)
Catalogue number
  • D68-10/084-2018E-PDF
Subject terms
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