NACI literature review on the comparative effectiveness and immunogenicity of subunit and split virus inactivated influenza vaccines in adults 65 years of age and older .: HP40-213/2018E-PDF

"Subunit and split virus inactivated influenza vaccines are two commonly used types of seasonal influenza vaccines, and continue to dominate the market in Canada. Although these two formulations of influenza vaccine have been available for many decades, NACI has not previously conducted a literature review to investigate the comparative vaccine effectiveness of these different formulations. A difference in vaccine effectiveness between these formulations would be especially important for older adults (65 years of age or older), since there is evidence that older adults experience more severe illness due to influenza and have reduced vaccine effectiveness compared to younger adults. To address this gap, NACI conducted a literature review to examine the vaccine effectiveness and immunogenicity of unadjuvanted, standard dose subunit inactivated influenza vaccines compared to unadjuvanted, standard dose split virus inactivated influenza vaccines in adults 65 years of age and older"--Executive summary, p. 3.

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Publication information
Department/Agency Canada. Public Health Agency of Canada.
Canada. National Advisory Committee on Immunization.
Title NACI literature review on the comparative effectiveness and immunogenicity of subunit and split virus inactivated influenza vaccines in adults 65 years of age and older .
Variant title At head of title: Advisory committee review, National Advisory Committee on Immunization (NACI)
Publication type Monograph
Language [English]
Other language editions [French]
Format Electronic
Electronic document
Note(s) Issued also in French under title: Revue de la littérature du CCNI sur l’efficacité comparative et l’immunogénicité du vaccin antigrippal inactivé sous unitaire et du vaccin antigrippal inactivé à virion fragmenté chez les adultes âgés de 65 ans et plus.
Cover title.
"Publication date: May 2018."
Prepared by: K. Young ... [et al.]. Cf. Acknowledgements.
Includes bibliographical references (p. 13-14).
Publishing information [Ottawa] : Public Health Agency of Canada, 2018.
Description 29 p.
ISBN 9780660264387
Catalogue number
  • HP40-213/2018E-PDF
Departmental catalogue number 180039
Subject terms Seniors
Immunization
Influenza
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